Leukemia cells accumulate DNA damage, but altered DNA repair mechanisms protect them from apoptosis. Gupta, Jean-Yves Masson, Tomasz Skorski DNA polymerase θ protects leukemia cells from metabolically induced DNA damage. Pomerantz, George Morton, Wayne Childers, Huaqing Zhao, Elisabeth M. Sykes, Katarzyna Piwocka, Emir Hadzijusufovic, Peter Valent, Richard T. Chitrala, Jessica Atkins, Malgorzata Drzewiecka, Wanjuan Feng, Joe Chan, Srinivas Chatla, Konstantin Golovine, Jaroslav Jelinek, Tomasz Sliwinski, Jayashri Ghosh, Ksenia Matlawska-Wasowska, Gurushankar Chandramouly, Reza Nejati, Mariusz Wasik, Stephen M. Maine, Tufts University and U.Umeshkumar Vekariya, Monika Toma, Margaret Nieborowska-Skorska, Bac Viet Le, Marie-Christine Caron, Anna-Mariya Kukuyan, Katherine Sullivan-Reed, Paulina Podszywalow-Bartnicka, Kumaraswamy N. Teaching the Genome Generation Short Course.Summer Student Program (undergrad & high school).The JAX Mouse Repository and Scientific Services are among the premier resources available for biomedical research.Neurobehavioral disorders: autism, addiction, depression.Neurobiology: blindness, Parkinson’s, Alzheimer’s, deafness, epilepsy, glaucoma, macular degeneration, neurodegenerative diseases.Metabolic diseases: atherosclerosis, cardiovascular disease, diabetes, high blood pressure, obesity, microbiome.Immunology: HIV-AIDS, anemia, autoimmunity, cancer immunology, immune disorders, lupus, transplant rejection.Developmental/reproductive biology: birth defects, Down syndrome, osteoporosis, fertility.Cancer: We are a National Cancer Institute designated Cancer Center focusing on cancer initiation, progression, prevention and therapies.JAX blends the brightest minds with state-of-the-art resources to accelerate discovery.Īreas of Discovery (75+ Principal Investigators, >250 Ph.D.s, M.D.s, and D.V.M.s): The Jackson Laboratory (JAX) leads the search to cure diseases rooted in our DNA.įounded in 1929, we are an NCI-designated Cancer Center since 1983 and an independent 501(c)3 nonprofit research organization with over 90 years of experience in genetics and genomics research. The Jackson Laboratory company descriptionĬancer.

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